Pronunciation: DEX-troe-meth-OR-fan/gwye-FEN-e-sin/FEN-ill-EF-rin
Generic Name: Dextromethorphan/Guaifenesin/Phenylephrine
Brand Name: Examples include Duraphen DM and Sinutuss DM
Duraphen DM Controlled-Release and Sustained-Release Tablets are used for:
Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Duraphen DM Controlled-Release and Sustained-Release Tablets are a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.
Do NOT use Duraphen DM Controlled-Release and Sustained-Release Tablets if:
- you are allergic to any ingredient in Duraphen DM Controlled-Release and Sustained-Release Tablets
- you have an enlarged prostate gland, severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
- you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using Duraphen DM Controlled-Release and Sustained-Release Tablets:
Some medical conditions may interact with Duraphen DM Controlled-Release and Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
- if you have a chronic cough, lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus
Some MEDICINES MAY INTERACT with Duraphen DM Controlled-Release and Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Duraphen DM Controlled-Release and Sustained-Release Tablets's side effects
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine because the risk of its side effects may be increased by Duraphen DM Controlled-Release and Sustained-Release Tablets
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Duraphen DM Controlled-Release and Sustained-Release Tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if Duraphen DM Controlled-Release and Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Duraphen DM Controlled-Release and Sustained-Release Tablets:
Use Duraphen DM Controlled-Release and Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Duraphen DM Controlled-Release and Sustained-Release Tablets by mouth with or without food.
- Drink plenty of water while taking Duraphen DM Controlled-Release and Sustained-Release Tablets.
- Swallow Duraphen DM Controlled-Release and Sustained-Release Tablets whole. Do not break, crush, or chew before swallowing. Some brands of Duraphen DM Controlled-Release and Sustained-Release Tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
- If you miss a dose of Duraphen DM Controlled-Release and Sustained-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Duraphen DM Controlled-Release and Sustained-Release Tablets.
Important safety information:
- Duraphen DM Controlled-Release and Sustained-Release Tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Duraphen DM Controlled-Release and Sustained-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not take appetite suppressants while you are taking Duraphen DM Controlled-Release and Sustained-Release Tablets without checking with your doctor.
- Duraphen DM Controlled-Release and Sustained-Release Tablets has phenylephrine and dextromethorphan in it. Before you start any new medicine, check the label to see if it has phenylephrine or dextromethorphan in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Do NOT exceed the recommended dose or take Duraphen DM Controlled-Release and Sustained-Release Tablets for longer than prescribed without checking with your doctor.
- If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
- If cough persists for more than 1 week or comes back, or is accompanied by a fever, rash, or persistent headache, contact your health care provider. A persistent cough could be a sign of a serious condition.
- Duraphen DM Controlled-Release and Sustained-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Duraphen DM Controlled-Release and Sustained-Release Tablets.
- Tell your doctor or dentist that you take Duraphen DM Controlled-Release and Sustained-Release Tablets before you receive any medical or dental care, emergency care, or surgery.
- Use Duraphen DM Controlled-Release and Sustained-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- Duraphen DM Controlled-Release and Sustained-Release Tablets should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Duraphen DM Controlled-Release and Sustained-Release Tablets while you are pregnant. It is not known if Duraphen DM Controlled-Release and Sustained-Release Tablets are found in breast milk. Do not breast-feed while taking Duraphen DM Controlled-Release and Sustained-Release Tablets.
Possible side effects of Duraphen DM Controlled-Release and Sustained-Release Tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Duraphen DM side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.
Proper storage of Duraphen DM Controlled-Release and Sustained-Release Tablets:
Store Duraphen DM Controlled-Release and Sustained-Release Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Duraphen DM Controlled-Release and Sustained-Release Tablets out of the reach of children and away from pets.
General information:
- If you have any questions about Duraphen DM Controlled-Release and Sustained-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
- Duraphen DM Controlled-Release and Sustained-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Duraphen DM Controlled-Release and Sustained-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Duraphen DM resources
- Duraphen DM Side Effects (in more detail)
- Duraphen DM Use in Pregnancy & Breastfeeding
- Duraphen DM Drug Interactions
- Duraphen DM Support Group
- 0 Reviews for Duraphen DM - Add your own review/rating
Compare Duraphen DM with other medications
- Cough and Nasal Congestion
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