Wednesday, 26 September 2012

Sennosides Granules



Pronunciation: SEN-oh-sides
Generic Name: Sennosides
Brand Name: Senokot


Sennosides Granules are used for:

Treating constipation.


Sennosides Granules are a stimulant laxative. It works by irritating bowel tissues, resulting in bowel movements.


Do NOT use Sennosides Granules if:


  • you are allergic to any ingredient in Sennosides Granules

  • you have had recent abdominal surgery or require immediate abdominal surgery

  • you have appendicitis; bleeding of the stomach, intestine, or rectum; or an obstruction in your intestines (fecal impaction)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Sennosides Granules:


Some medical conditions may interact with Sennosides Granules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have congestive heart failure, you are experiencing nausea or vomiting, or you have undiagnosed stomach pain

Some MEDICINES MAY INTERACT with Sennosides Granules. However, no specific interactions with Sennosides Granules are known at this time.


Ask your health care provider if Sennosides Granules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Sennosides Granules:


Use Sennosides Granules as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Sennosides Granules by mouth with or without food.

  • Take Sennosides Granules with a full glass of water (8 oz/240 mL). Drinking extra fluids while you are taking Sennosides Granules are recommended. Check with your doctor for instructions.

  • It is best to take Sennosides Granules at bedtime.

  • If you miss a dose of Sennosides Granules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sennosides Granules.



Important safety information:


  • A bowel movement usually occurs in 6 to 12 hours.

  • Do not use for longer than 1 week without checking with your doctor.

  • Using Sennosides Granules for a long time may result in loss of normal bowel function.

  • Do not take additional laxatives or stool softeners with Sennosides Granules unless directed by your doctor.

  • If you notice a sudden change in bowel habits that lasts for 2 weeks or more, stop using Sennosides Granules and check with your doctor.

  • Sennosides Granules may discolor the urine pink to red, or yellow to brown.

  • Sennosides Granules should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sennosides Granules while you are pregnant. It is not known if Sennosides Granules are found in breast milk. If you are or will be breast-feeding while you use Sennosides Granules, check with your doctor. Discuss any possible risks to your baby.

Overuse of laxatives can lead to a DEPENDENCE on laxatives to have a bowel movement. In severe overuse cases, some laxatives have caused damage to the intestines and bowel.



Possible side effects of Sennosides Granules:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Abdominal discomfort or cramping; diarrhea; nausea.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney inflammation; poor bowel function; rectal bleeding.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Sennosides side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately.


Proper storage of Sennosides Granules:

Store Sennosides Granules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep Sennosides Granules out of the reach of children and away from pets.


General information:


  • If you have any questions about Sennosides Granules, please talk with your doctor, pharmacist, or other health care provider.

  • Sennosides Granules are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sennosides Granules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sennosides resources


  • Sennosides Side Effects (in more detail)
  • Sennosides Use in Pregnancy & Breastfeeding
  • Drug Images
  • Sennosides Drug Interactions
  • Sennosides Support Group
  • 6 Reviews for Sennosides - Add your own review/rating


Compare Sennosides with other medications


  • Bowel Preparation
  • Constipation

Saturday, 22 September 2012

Aqueous Iodine Oral Solution BP





1. Name Of The Medicinal Product



Aqueous Iodine Oral Solution BP


2. Qualitative And Quantitative Composition



Iodine BP 5.0% w/v



Potassium Iodide BP 10.0% w/v



3. Pharmaceutical Form



Oral Solution



4. Clinical Particulars



4.1 Therapeutic Indications



For use in the pre-operative management of hyperthyroidism.



4.2 Posology And Method Of Administration



Oral.



Dose: adults, children and the elderly: 0.1 – 0.3ml well diluted in milk or water.



Dosage schedule: to be taken three times a day for six days.



4.3 Contraindications



Contraindicated for patients hypersensitive to iodine or iodides, and use in pregnancy and lactation.



4.4 Special Warnings And Precautions For Use



Should not be used for long term treatment.



Dispensing pack-not for retail sale.



Keep all medicines away from children.



Use with caution in children.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



Administration of this product may interfere with tests of thyroid function.



4.6 Pregnancy And Lactation



Not to be used during pregnancy and lactation. Iodides cross the placenta and are excreted in breast milk. There is a possibility of goitre in infants of mothers taking iodides.



4.7 Effects On Ability To Drive And Use Machines



None known.



4.8 Undesirable Effects



May cause allergic reactions, including urticaria, angioedema, cutaneous haemorrhage or purpuras, fever, arthralgia, lymphadenopathy and eosinophilia, coryza-like symptoms, headache, lachrymation, conjunctivitis, laryngitis, bronchitis, and pain in the salivary glands. In addition to the above, use may lead to adverse effects on the mouth such as metallic taste, increased salivation, burning or pain. Swelling and inflammation of the throat, acneform skin disorders, depression, insomnia, impotence and diarrhoea (which may be bloody) can also result.



4.9 Overdose



Symptoms of acute poisoning from ingestion of iodine include a disagreeable metallic taste, vomiting, abdominal pain and diarrhoea may occur. Renal failure may occur 1-3 days later. Death may be caused by circulatory failure, swelling of the epiglottis causing asphyxia, aspiration, pneumonia or pulmonary oedema. Oesophageal stricture may occur if the patient survives the acute stage. The fatal dose of iodine is 2 to 3g. Symptomatic treatment for allergic reactions and iodism may be required, although symptoms usually subside rapidly when administration of iodine or iodide is stopped. In acute poisoning copious draughts of milk and starch mucilage should be given. If there is no oesophageal damage the stomach may be emptied by aspiration and lavage with dilute starch mucilage or a 1% solution of sodium thiosulphate. Use of gastric lavage with activated charcoal has also been suggested. Electrolyte and water losses should be replaced and the circulation should be maintained. Pethidine or morphine sulphate may be given for pain, under medical supervision. A tracheotomy may become necessary.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Iodine and iodides are used in the pre-operative treatment of hyperthyroidism in conjunction with antithyroid agents. The patient is rendered euthyroid with an antithyroid agent and iodine or iodides are added to the therapy before subtotal thyroidectomy. Iodine aqueous solution is given to render the thyroid firm and avoid the increased vascularity and friability with increased risk of haemorrhage that may result from the use of an antithyroid agent alone.



5.2 Pharmacokinetic Properties



Iodine is converted to iodide, which is trapped in the thyroid gland.



Iodides are excreted mainly in the urine with smaller amounts excreted in the faeces, sweat and saliva. They cross the placenta and are excreted in breast milk.



5.3 Preclinical Safety Data



No data of relevance which is additional to that included on other sections of the SPC.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Purified water BP



6.2 Incompatibilities



None known.



6.3 Shelf Life



100ml: 36 months unopened.



500ml: 36 months unopened.



6.4 Special Precautions For Storage



Store below 25°C.



6.5 Nature And Contents Of Container



100ml: amber glass bottle, plastic cap.



500ml: amber glass bottle, plastic cap.



6.6 Special Precautions For Disposal And Other Handling



None



7. Marketing Authorisation Holder



Thornton & Ross Ltd.,



Linthwaite Laboratories



Huddersfield



HD7 5QH



8. Marketing Authorisation Number(S)



PL 00240/6170R



9. Date Of First Authorisation/Renewal Of The Authorisation



04.12.98



10. Date Of Revision Of The Text



12.11.01



11 DOSIMETRY (IF APPLICABLE)


Not Applicable



12 INSTRUCTIONS FOR PREPARATION OF RADIOPHARMACEUTICALS (IF APPLICABLE)


Not Applicable




Friday, 21 September 2012

levofloxacin Ophthalmic



lee-voe-FLOX-a-sin


Commonly used brand name(s)

In the U.S.


  • Iquix

  • Quixin

Available Dosage Forms:


  • Solution

Therapeutic Class: Antibiotic


Chemical Class: Fluoroquinolone


Uses For levofloxacin


Ophthalmic levofloxacin is used in the eye to treat bacterial infections of the eye. Ophthalmic levofloxacin works by killing bacteria.


levofloxacin is available only with your doctor's prescription.


Before Using levofloxacin


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For levofloxacin, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to levofloxacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Use is not recommended in infants under 1 year of age. In children older than 1 year, levofloxacin is not expected to cause different side effects or problems than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of levofloxacin in the elderly with use in other age groups, levofloxacin is not expected to cause different side effects or problems in older people than it does in younger adults.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking levofloxacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using levofloxacin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Cisapride

  • Dronedarone

  • Mesoridazine

  • Pimozide

  • Sparfloxacin

  • Thioridazine

Using levofloxacin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Acecainide

  • Acetohexamide

  • Alfuzosin

  • Amiodarone

  • Amitriptyline

  • Amoxapine

  • Apomorphine

  • Arsenic Trioxide

  • Asenapine

  • Astemizole

  • Azimilide

  • Azithromycin

  • Benfluorex

  • Bretylium

  • Chloroquine

  • Chlorpromazine

  • Chlorpropamide

  • Ciprofloxacin

  • Citalopram

  • Clarithromycin

  • Clomipramine

  • Clozapine

  • Crizotinib

  • Dasatinib

  • Desipramine

  • Disopyramide

  • Dofetilide

  • Dolasetron

  • Droperidol

  • Erythromycin

  • Flecainide

  • Fluconazole

  • Gatifloxacin

  • Gemifloxacin

  • Gliclazide

  • Glimepiride

  • Glipizide

  • Gliquidone

  • Glyburide

  • Granisetron

  • Guar Gum

  • Halofantrine

  • Haloperidol

  • Ibutilide

  • Iloperidone

  • Imipramine

  • Insulin

  • Insulin Aspart, Recombinant

  • Insulin Glulisine

  • Insulin Lispro, Recombinant

  • Lapatinib

  • Lopinavir

  • Lumefantrine

  • Mefloquine

  • Metformin

  • Methadone

  • Miglitol

  • Moricizine

  • Moxifloxacin

  • Nilotinib

  • Norfloxacin

  • Nortriptyline

  • Octreotide

  • Ofloxacin

  • Paliperidone

  • Pazopanib

  • Perflutren Lipid Microsphere

  • Perphenazine

  • Posaconazole

  • Procainamide

  • Prochlorperazine

  • Promethazine

  • Propafenone

  • Protriptyline

  • Quetiapine

  • Quinidine

  • Quinine

  • Ranolazine

  • Salmeterol

  • Saquinavir

  • Sematilide

  • Sodium Phosphate

  • Sodium Phosphate, Dibasic

  • Sodium Phosphate, Monobasic

  • Solifenacin

  • Sorafenib

  • Sotalol

  • Sunitinib

  • Tedisamil

  • Telavancin

  • Telithromycin

  • Terfenadine

  • Tetrabenazine

  • Theophylline

  • Tolazamide

  • Tolbutamide

  • Toremifene

  • Trazodone

  • Trifluoperazine

  • Trimipramine

  • Troglitazone

  • Vandetanib

  • Vardenafil

  • Vemurafenib

  • Voriconazole

  • Warfarin

  • Ziprasidone

Using levofloxacin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Betamethasone

  • Corticotropin

  • Cortisone

  • Cosyntropin

  • Deflazacort

  • Dexamethasone

  • Fludrocortisone

  • Fluocortolone

  • Hydrocortisone

  • Methylprednisolone

  • Paramethasone

  • Prednisolone

  • Prednisone

  • Triamcinolone

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Proper Use of levofloxacin


Dosing


The dose of levofloxacin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of levofloxacin. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


To use levofloxacin ophthalmic solution (eye drops):


  • First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.

  • If you think you did not get the drop of medicine into your eyes properly, use another drop.

  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

  • For ophthalmic solution dosage form:
    • For bacterial conjunctivitis:
      • Adults and children 1 year of age and older—Days 1 and 2: Put one to two drops in the affected eye(s) every two hours while awake. Do not put drops in more than 8 times a day. Days 3 through 7: Put one to two drops in the affected eye(s) every 4 hours while awake. Do not put drops in more than 4 times a day.

      • Infants and children up to 1 year of age—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of levofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using levofloxacin


If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.


levofloxacin may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.


levofloxacin Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • voice changes

  • body aches or pain

  • congestion

  • dryness or soreness of throat

  • runny nose

  • swelling of the eyelid

  • tender, swollen glands in neck

  • trouble in swallowing

  • Itching, pain, redness or swelling of eye or eyelid

  • watering of eyes

  • decreased vision

  • fever

  • feeling of having something in the eye

  • headache

  • hoarseness

  • eye burning, dryness, itching, or pain

  • increased sensitivity of eyes to light

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More levofloxacin Ophthalmic resources


  • Levofloxacin Ophthalmic Use in Pregnancy & Breastfeeding
  • Levofloxacin Ophthalmic Support Group
  • 0 Reviews for Levofloxacin Ophthalmic - Add your own review/rating


  • levofloxacin ophthalmic Concise Consumer Information (Cerner Multum)

  • Iquix Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Iquix Prescribing Information (FDA)

  • Quixin Prescribing Information (FDA)

  • Quixin eent Monograph (AHFS DI)

  • Quixin Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare levofloxacin Ophthalmic with other medications


  • Conjunctivitis, Bacterial
  • Ophthalmic Surgery

Ventricular Fibrillation Medications


Definition of Ventricular Fibrillation:

A disorganised chaotic contraction of the ventricle that fails to effectively eject blood from the ventricle.


During ventricular fibrillation the patient is unconscious and will die if emergency intervention is not undertaken

Drugs associated with Ventricular Fibrillation

The following drugs and medications are in some way related to, or used in the treatment of Ventricular Fibrillation. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Learn more about Ventricular Fibrillation





Drug List:

Thursday, 20 September 2012

Hypertensive Heart without CHF and Renal Disease Medications


There are currently no drugs listed for "Hypertensive Heart without CHF and Renal Disease".

Learn more about Hypertensive Heart without CHF and Renal Disease





Drug List:

Visine Maximum Redness Relief


Generic Name: tetrahydrozoline ophthalmic (TE tra hye DROZ oh leen)

Brand Names: Altazine, Geneye Extra, Geneyes, Opti-Clear, Optigene 3, Redness Relief, Redness Relief Original, Visine, Visine Maximum Redness Relief, Vision Clear


What is Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?

Tetrahydrozoline ophthalmic narrows the blood vessels (veins and arteries) in your eyes.


Tetrahydrozoline ophthalmic (for the eyes) is used to relieve redness, burning, irritation, and dryness of the eyes caused by wind, sun, and other minor irritants.

Tetrahydrozoline ophthalmic may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use tetrahydrozoline ophthalmic without medical advice if you have glaucoma. Do not use this medication while wearing contact lenses. Tetrahydrozoline ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using tetrahydrozoline ophthalmic before putting your contact lenses in. Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. Do not use tetrahydrozoline ophthalmic more often than recommended, or use it for longer than 48 to 72 hours without medical advice. Long-term use of this medication may damage the blood vessels in the eyes. Call your doctor if your symptoms do not improve or if they get worse.

What should I discuss with my healthcare provider before using Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use tetrahydrozoline ophthalmic without medical advice if you have glaucoma.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:



  • heart disease or coronary artery disease;




  • high blood pressure;




  • diabetes; or




  • a thyroid disorder.




FDA pregnancy category C. It is not known whether tetrahydrozoline ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether tetrahydrozoline nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child without a doctor's advice.

How should I use Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Do not use tetrahydrozoline ophthalmic more often than recommended, or use it for longer than 48 to 72 hours without medical advice. Long-term use of this medication may damage the blood vessels in the eyes. Call your doctor if your symptoms do not improve or if they get worse. Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using tetrahydrozoline before putting your contact lenses in. Wash your hands before and after using the eye drops.

To apply the eye drops:



  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.




  • Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.




  • Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.




Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it.


Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?


Since tetrahydrozoline ophthalmic is used on an as needed basis, you are not likely to miss a dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use other eye medications during treatment with tetrahydrozoline ophthalmic unless your doctor tells you to.

Visine Maximum Redness Relief (tetrahydrozoline ophthalmic) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tetrahydrozoline ophthalmic and call your doctor at once if you have a serious side effect such as:

  • severe burning, stinging, swelling, or other irritation after using the eye drops;




  • fast or pounding heartbeats; or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).



Less serious side effects may include:



  • burning, stinging, pain, or increased redness of the eye;




  • tearing or blurred vision;




  • nausea;




  • nervousness, dizziness, drowsiness;




  • sleep problems (insomnia); or




  • headache.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Tell your doctor about all other medicines you use, especially:



  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate); or




  • a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.



This list is not complete and other drugs may interact with tetrahydrozoline ophthalmic. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Visine Maximum Redness Relief resources


  • Visine Maximum Redness Relief Side Effects (in more detail)
  • Visine Maximum Redness Relief Use in Pregnancy & Breastfeeding
  • Visine Maximum Redness Relief Drug Interactions
  • 0 Reviews for Visine Maximum Redness Relief - Add your own review/rating


  • Clarinex Monograph (AHFS DI)

  • Visine Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Visine Maximum Redness Relief with other medications


  • Eye Dryness/Redness


Where can I get more information?


  • Your pharmacist can provide more information about tetrahydrozoline ophthalmic.

See also: Visine Maximum Redness Relief side effects (in more detail)


Sunday, 16 September 2012

carbetapentane, diphenhydramine, and phenylephrine


Generic Name: carbetapentane, diphenhydramine, and phenylephrine (car bay tah PEN tane, die fen HIGH dra meen, and feh nill EH frin)

Brand names: D-Tann CT, Dytan-CS, Uni-Tann CS, Dytan-CD, D-Tann CD


What is carbetapentane, diphenhydramine, and phenylephrine?

Carbetapentane is a cough suppressant.


Diphenhydramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Diphenhydramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.


Phenylephrine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. Constriction of blood vessels in the sinuses and nose decreases congestion.


Carbetapentane, diphenhydramine, and phenylephrine is used to treat cough and nasal congestion associated with allergies or the common cold.


Carbetapentane, diphenhydramine, and phenylephrine may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about carbetapentane, diphenhydramine, and phenylephrine?


Use caution when driving, operating machinery, or performing other hazardous activities. Carbetapentane, diphenhydramine, and phenylephrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbetapentane, diphenhydramine, and phenylephrine.

What should I discuss with my healthcare provider before taking carbetapentane, diphenhydramine, and phenylephrine?


Do not take carbetapentane, diphenhydramine, and phenylephrine if you have taken selegiline (Carbex, Eldepryl) or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have



  • epilepsy or another seizure disorder;




  • been diagnosed with sleep apnea (periods of not breathing during sleep);




  • thyroid problems;




  • asthma, emphysema, or chronic obstructive pulmonary disease (COPD);




  • gallbladder disease;




  • a head injury;




  • Addison's disease;




  • diabetes;




  • glaucoma;




  • an ulcer or an obstruction in the stomach;




  • bladder problems or difficulty urinating;



  • an enlarged prostate;


  • high blood pressure, irregular heartbeats, or any type of heart disease;



  • kidney problems; or

  • liver problems.

You may not be able to take carbetapentane, diphenhydramine, and phenylephrine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.


It is not known whether this medication will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Carbetapentane, diphenhydramine, and phenylephrine may pass into breast milk and be harmful to a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from carbetapentane, diphenhydramine, and phenylephrine. You may need a lower dose of this medication.

How should I take carbetapentane, diphenhydramine, and phenylephrine?


Take carbetapentane, diphenhydramine, and phenylephrine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of carbetapentane, diphenhydramine, and phenylephrine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.


Do not take more of this medication than is recommended. An overdose of this medication can cause serious harm.

Do not take carbetapentane, diphenhydramine, and phenylephrine for longer than is prescribed. If your symptoms do not improve, if they get worse, or if they are accompanied by fever, talk to your doctor.


Store carbetapentane, diphenhydramine, and phenylephrine at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.


What happens if I overdose?


Seek emergency medical attention if an overdose is suspected.

Symptoms of a carbetapentane, diphenhydramine, and phenylephrine overdose include dryness of the mouth, large pupils, flushing, nausea, vomiting, hyperactivity, or hallucinations.


What should I avoid while taking carbetapentane, diphenhydramine, and phenylephrine?


Use caution when driving, operating machinery, or performing other hazardous activities. Carbetapentane, diphenhydramine, and phenylephrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbetapentane, diphenhydramine, and phenylephrine.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking carbetapentane, diphenhydramine, and phenylephrine without first talking to your doctor or pharmacist. Other medications may also contain carbetapentane, phenylephrine, pyrilamine or other similar drugs. You may accidentally take too much of these medicines.


Carbetapentane, diphenhydramine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if carbetapentane, diphenhydramine, and phenylephrine is taken with any of these medications.


Carbetapentane, diphenhydramine, and phenylephrine side effects


Serious side effects are unlikely to occur. Stop taking carbetapentane, diphenhydramine, and phenylephrine and seek emergency medical attention if an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) is experienced.

Other, less serious side effects may be more likely to occur. Continue to take carbetapentane, diphenhydramine, and phenylephrine and talk to your doctor or try another similar medication if you experience



  • dryness of the eyes, nose, or mouth;




  • drowsiness or dizziness;




  • blurred vision;




  • difficulty urinating; or




  • excitation in children.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


Carbetapentane, diphenhydramine, and phenylephrine Dosing Information


Usual Adult Dose for Allergic Rhinitis:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Adult Dose for Cold Symptoms:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Adult Dose for Cough and Nasal Congestion:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Allergic Rhinitis:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Cold Symptoms:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Cough and Nasal Congestion:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.


What other drugs will affect carbetapentane, diphenhydramine, and phenylephrine?


Do not take carbetapentane, diphenhydramine, and phenylephrine if you have taken selegiline (Carbex, Eldepryl) or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking carbetapentane, diphenhydramine, and phenylephrine without first talking to your doctor or pharmacist. Other medications may also contain carbetapentane, phenylephrine, pyrilamine or other similar drugs. You may accidentally take too much of these medicines.


Carbetapentane, diphenhydramine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if carbetapentane, diphenhydramine, and phenylephrine is taken with any of these medications.


Drugs other than those listed here may also interact with carbetapentane, diphenhydramine, and phenylephrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.



More carbetapentane, diphenhydramine, and phenylephrine resources


  • Carbetapentane, diphenhydramine, and phenylephrine Side Effects (in more detail)
  • Carbetapentane, diphenhydramine, and phenylephrine Use in Pregnancy & Breastfeeding
  • Carbetapentane, diphenhydramine, and phenylephrine Drug Interactions
  • Carbetapentane, diphenhydramine, and phenylephrine Support Group
  • 1 Review for Carbetapentane, diphenhydramine, and phenylephrine - Add your own review/rating


Compare carbetapentane, diphenhydramine, and phenylephrine with other medications


  • Cold Symptoms
  • Cough and Nasal Congestion
  • Hay Fever


Where can I get more information?


  • Your pharmacist has additional information about carbetapentane, diphenhydramine, and phenylephrine written for health professionals that you may read.

See also: carbetapentane, diphenhydramine, and phenylephrine side effects (in more detail)