Thursday, 20 September 2012

Hypertensive Heart without CHF and Renal Disease Medications


There are currently no drugs listed for "Hypertensive Heart without CHF and Renal Disease".

Learn more about Hypertensive Heart without CHF and Renal Disease





Drug List:

Visine Maximum Redness Relief


Generic Name: tetrahydrozoline ophthalmic (TE tra hye DROZ oh leen)

Brand Names: Altazine, Geneye Extra, Geneyes, Opti-Clear, Optigene 3, Redness Relief, Redness Relief Original, Visine, Visine Maximum Redness Relief, Vision Clear


What is Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?

Tetrahydrozoline ophthalmic narrows the blood vessels (veins and arteries) in your eyes.


Tetrahydrozoline ophthalmic (for the eyes) is used to relieve redness, burning, irritation, and dryness of the eyes caused by wind, sun, and other minor irritants.

Tetrahydrozoline ophthalmic may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use tetrahydrozoline ophthalmic without medical advice if you have glaucoma. Do not use this medication while wearing contact lenses. Tetrahydrozoline ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using tetrahydrozoline ophthalmic before putting your contact lenses in. Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. Do not use tetrahydrozoline ophthalmic more often than recommended, or use it for longer than 48 to 72 hours without medical advice. Long-term use of this medication may damage the blood vessels in the eyes. Call your doctor if your symptoms do not improve or if they get worse.

What should I discuss with my healthcare provider before using Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use tetrahydrozoline ophthalmic without medical advice if you have glaucoma.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:



  • heart disease or coronary artery disease;




  • high blood pressure;




  • diabetes; or




  • a thyroid disorder.




FDA pregnancy category C. It is not known whether tetrahydrozoline ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether tetrahydrozoline nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child without a doctor's advice.

How should I use Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Do not use tetrahydrozoline ophthalmic more often than recommended, or use it for longer than 48 to 72 hours without medical advice. Long-term use of this medication may damage the blood vessels in the eyes. Call your doctor if your symptoms do not improve or if they get worse. Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using tetrahydrozoline before putting your contact lenses in. Wash your hands before and after using the eye drops.

To apply the eye drops:



  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.




  • Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.




  • Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.




Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it.


Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?


Since tetrahydrozoline ophthalmic is used on an as needed basis, you are not likely to miss a dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Do not use other eye medications during treatment with tetrahydrozoline ophthalmic unless your doctor tells you to.

Visine Maximum Redness Relief (tetrahydrozoline ophthalmic) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tetrahydrozoline ophthalmic and call your doctor at once if you have a serious side effect such as:

  • severe burning, stinging, swelling, or other irritation after using the eye drops;




  • fast or pounding heartbeats; or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).



Less serious side effects may include:



  • burning, stinging, pain, or increased redness of the eye;




  • tearing or blurred vision;




  • nausea;




  • nervousness, dizziness, drowsiness;




  • sleep problems (insomnia); or




  • headache.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Visine Maximum Redness Relief (tetrahydrozoline ophthalmic)?


Tell your doctor about all other medicines you use, especially:



  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate); or




  • a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.



This list is not complete and other drugs may interact with tetrahydrozoline ophthalmic. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Visine Maximum Redness Relief resources


  • Visine Maximum Redness Relief Side Effects (in more detail)
  • Visine Maximum Redness Relief Use in Pregnancy & Breastfeeding
  • Visine Maximum Redness Relief Drug Interactions
  • 0 Reviews for Visine Maximum Redness Relief - Add your own review/rating


  • Clarinex Monograph (AHFS DI)

  • Visine Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Visine Maximum Redness Relief with other medications


  • Eye Dryness/Redness


Where can I get more information?


  • Your pharmacist can provide more information about tetrahydrozoline ophthalmic.

See also: Visine Maximum Redness Relief side effects (in more detail)


Sunday, 16 September 2012

carbetapentane, diphenhydramine, and phenylephrine


Generic Name: carbetapentane, diphenhydramine, and phenylephrine (car bay tah PEN tane, die fen HIGH dra meen, and feh nill EH frin)

Brand names: D-Tann CT, Dytan-CS, Uni-Tann CS, Dytan-CD, D-Tann CD


What is carbetapentane, diphenhydramine, and phenylephrine?

Carbetapentane is a cough suppressant.


Diphenhydramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Diphenhydramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.


Phenylephrine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. Constriction of blood vessels in the sinuses and nose decreases congestion.


Carbetapentane, diphenhydramine, and phenylephrine is used to treat cough and nasal congestion associated with allergies or the common cold.


Carbetapentane, diphenhydramine, and phenylephrine may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about carbetapentane, diphenhydramine, and phenylephrine?


Use caution when driving, operating machinery, or performing other hazardous activities. Carbetapentane, diphenhydramine, and phenylephrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbetapentane, diphenhydramine, and phenylephrine.

What should I discuss with my healthcare provider before taking carbetapentane, diphenhydramine, and phenylephrine?


Do not take carbetapentane, diphenhydramine, and phenylephrine if you have taken selegiline (Carbex, Eldepryl) or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have



  • epilepsy or another seizure disorder;




  • been diagnosed with sleep apnea (periods of not breathing during sleep);




  • thyroid problems;




  • asthma, emphysema, or chronic obstructive pulmonary disease (COPD);




  • gallbladder disease;




  • a head injury;




  • Addison's disease;




  • diabetes;




  • glaucoma;




  • an ulcer or an obstruction in the stomach;




  • bladder problems or difficulty urinating;



  • an enlarged prostate;


  • high blood pressure, irregular heartbeats, or any type of heart disease;



  • kidney problems; or

  • liver problems.

You may not be able to take carbetapentane, diphenhydramine, and phenylephrine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.


It is not known whether this medication will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Carbetapentane, diphenhydramine, and phenylephrine may pass into breast milk and be harmful to a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from carbetapentane, diphenhydramine, and phenylephrine. You may need a lower dose of this medication.

How should I take carbetapentane, diphenhydramine, and phenylephrine?


Take carbetapentane, diphenhydramine, and phenylephrine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of carbetapentane, diphenhydramine, and phenylephrine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.


Do not take more of this medication than is recommended. An overdose of this medication can cause serious harm.

Do not take carbetapentane, diphenhydramine, and phenylephrine for longer than is prescribed. If your symptoms do not improve, if they get worse, or if they are accompanied by fever, talk to your doctor.


Store carbetapentane, diphenhydramine, and phenylephrine at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.


What happens if I overdose?


Seek emergency medical attention if an overdose is suspected.

Symptoms of a carbetapentane, diphenhydramine, and phenylephrine overdose include dryness of the mouth, large pupils, flushing, nausea, vomiting, hyperactivity, or hallucinations.


What should I avoid while taking carbetapentane, diphenhydramine, and phenylephrine?


Use caution when driving, operating machinery, or performing other hazardous activities. Carbetapentane, diphenhydramine, and phenylephrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbetapentane, diphenhydramine, and phenylephrine.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking carbetapentane, diphenhydramine, and phenylephrine without first talking to your doctor or pharmacist. Other medications may also contain carbetapentane, phenylephrine, pyrilamine or other similar drugs. You may accidentally take too much of these medicines.


Carbetapentane, diphenhydramine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if carbetapentane, diphenhydramine, and phenylephrine is taken with any of these medications.


Carbetapentane, diphenhydramine, and phenylephrine side effects


Serious side effects are unlikely to occur. Stop taking carbetapentane, diphenhydramine, and phenylephrine and seek emergency medical attention if an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) is experienced.

Other, less serious side effects may be more likely to occur. Continue to take carbetapentane, diphenhydramine, and phenylephrine and talk to your doctor or try another similar medication if you experience



  • dryness of the eyes, nose, or mouth;




  • drowsiness or dizziness;




  • blurred vision;




  • difficulty urinating; or




  • excitation in children.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


Carbetapentane, diphenhydramine, and phenylephrine Dosing Information


Usual Adult Dose for Allergic Rhinitis:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Adult Dose for Cold Symptoms:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Adult Dose for Cough and Nasal Congestion:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 ml oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release
5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Allergic Rhinitis:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Cold Symptoms:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.

Usual Pediatric Dose for Cough and Nasal Congestion:

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-7.5 mg/5 mL oral suspension, extended release:
carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release:
2 years to 6 years to >=12 years: 5 to 10 mL orally every 12 hours.

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-15 mg/5 ml oral suspension, extended release

carbetapentane/diphenhydramine/phenylephrine 30 mg-25 mg-10 mg oral tablet, extended release and chewable, extended release:
6 years to >=12 years 1 to 2 tablets orally every 12 hours.


What other drugs will affect carbetapentane, diphenhydramine, and phenylephrine?


Do not take carbetapentane, diphenhydramine, and phenylephrine if you have taken selegiline (Carbex, Eldepryl) or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking carbetapentane, diphenhydramine, and phenylephrine without first talking to your doctor or pharmacist. Other medications may also contain carbetapentane, phenylephrine, pyrilamine or other similar drugs. You may accidentally take too much of these medicines.


Carbetapentane, diphenhydramine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if carbetapentane, diphenhydramine, and phenylephrine is taken with any of these medications.


Drugs other than those listed here may also interact with carbetapentane, diphenhydramine, and phenylephrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.



More carbetapentane, diphenhydramine, and phenylephrine resources


  • Carbetapentane, diphenhydramine, and phenylephrine Side Effects (in more detail)
  • Carbetapentane, diphenhydramine, and phenylephrine Use in Pregnancy & Breastfeeding
  • Carbetapentane, diphenhydramine, and phenylephrine Drug Interactions
  • Carbetapentane, diphenhydramine, and phenylephrine Support Group
  • 1 Review for Carbetapentane, diphenhydramine, and phenylephrine - Add your own review/rating


Compare carbetapentane, diphenhydramine, and phenylephrine with other medications


  • Cold Symptoms
  • Cough and Nasal Congestion
  • Hay Fever


Where can I get more information?


  • Your pharmacist has additional information about carbetapentane, diphenhydramine, and phenylephrine written for health professionals that you may read.

See also: carbetapentane, diphenhydramine, and phenylephrine side effects (in more detail)


Saturday, 15 September 2012

Lecithin Natural


Generic Name: lecithin (LEH sih thin)

Brand Names: Lecithin Natural, Lecithin-Softgels, Soya Lecithin


What is Lecithin Natural (lecithin)?

The use of lecithin in cultural and traditional settings may differ from concepts accepted by current Western medicine. When considering the use of herbal supplements, consultation with a primary health care professional is advisable. Additionally, consultation with a practitioner trained in the uses of herbal/health supplements may be beneficial, and coordination of treatment among all health care providers involved may be advantageous.


Lecithin is also known as lecithol, vitellin, kelecin, and granulestin. Lecithin is a naturally occurring substance found in beef liver, steak, eggs, peanuts, cauliflower, and oranges. Commercial lecithin products usually come from soybeans, egg yolk, or brain tissue.


Lecithin has been used in the treatment and/or prevention of high cholesterol levels, neurologic disorders, and liver ailments.


Lecithin has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of lecithin may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. There have been instances where herbal/health supplements have been sold which were contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.


Lecithin may also have uses other than those listed in this product guide.


What is the most important information I should know about Lecithin Natural (lecithin)?


Lecithin has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of lecithin may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. There have been instances where herbal/health supplements have been sold which were contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.


Who should not take Lecithin Natural (lecithin)?


Talk to your doctor before taking lecithin if you have any other medical conditions, allergies, or if you take other medicines or herbal/health supplements. Lecithin may not be recommended in some situations.


Do not take lecithin without first talking to your doctor if you are pregnant or could become pregnant. Lecithin is generally not recommended for use during pregnancy. Do not take lecithin without first talking to your doctor if you are breast-feeding a baby. There is no information available regarding the use of lecithin by children. Do not give any herbal/health supplement to a child without first talking to the child's doctor.

How should I take Lecithin Natural (lecithin)?


The use of lecithin in cultural and traditional settings may differ from concepts accepted by current Western medicine. When considering the use of herbal supplements, consultation with a primary health care professional is advisable. Additionally, consultation with a practitioner trained in the uses of herbal/health supplements may be beneficial, and coordination of treatment among all health care providers involved may be advantageous.


If you choose to use lecithin, use it as directed on the package or as directed by your doctor, pharmacist, or other health care provider.


Standardized extracts, tinctures, and solid formulations of herbal/health supplements may provide a more reliable dose of the product.


Lecithin is available in pill, granule, paste, and liquid formulations. Other formulations may also be available.


Do not take more of this product than is directed. Do not use different formulations (e.g., tablets, liquid, and others) of lecithin at the same time, unless specifically directed to do so by a health care professional. Using different formulations together increases the risk of an overdose of lecithin.

Store lecithin as directed on the package. In general, lecithin should be protected from light and moisture.


What happens if I miss a dose?


No information is available regarding a missed dose of lecithin. Consult your doctor, pharmacist, or health care provider if you require further information.


What happens if I overdose?


Seek emergency medical attention.

Symptoms of a lecithin overdose are not known.


What should I avoid while taking Lecithin Natural (lecithin)?


There are no known restrictions on food, beverages, or activity while taking lecithin, unless otherwise directed by your health care provider.


Lecithin Natural (lecithin) side effects


Although uncommon, allergic reactions to lecithin have been reported. Stop taking lecithin and seek emergency medical attention if you experience symptoms of a serious allergic reaction including difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives.

Other less serious side effects have also been infrequently reported. Talk to your doctor or pharmacist if you experience



  • decreased appetite,




  • nausea, or




  • increased salivation.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Lecithin Natural (lecithin)?


There are no reported interactions between lecithin and other medications. Talk to your doctor, pharmacist, or health care provider before taking any prescription or over-the-counter medicines or other herbal/health supplements.



More Lecithin Natural resources


  • Lecithin Natural Support Group
  • 0 Reviews for Lecithin Natural - Add your own review/rating


  • Lecithin Natural MedFacts for Professionals (Wolters Kluwer)

  • Lecithin Natural MedFacts for Consumers (Wolters Kluwer)

  • Lecithin



Compare Lecithin Natural with other medications


  • Herbal Supplementation


Where can I get more information?


  • Your doctor, pharmacist, or health care provider may have more information about lecithin.


Friday, 14 September 2012

Autoplex T


Generic Name: anti-inhibitor coagulant complex (an TEE in HIB i tor koe AG yoo lant KOM plex)

Brand Names: Autoplex T, Feiba NF, Feiba VH Immuno


What is Autoplex T (anti-inhibitor coagulant complex)?

Anti-inhibitor coagulant complex is made from proteins normally found in human blood that allow the blood to clot.


Anti-inhibitor coagulant complex is used to treat or prevent bleeding in people with hemophilia A or B and Factor VIII inhibitors.


Anti-inhibitor coagulant complex may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Autoplex T (anti-inhibitor coagulant complex)?


You should not use anti-inhibitor coagulant complex if you are allergic to it.

Before using this medication, tell your doctor if you have coronary artery disease or a history of heart attack, stroke, or blood clot.


Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.


Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.


Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder.

What should I discuss with my healthcare provider before using Autoplex T (anti-inhibitor coagulant complex)?


You should not use anti-inhibitor coagulant complex if you are allergic to it.

To make sure you can safely use anti-inhibitor coagulant complex, tell your doctor if you have any of these other conditions:



  • coronary artery disease; or




  • history of heart attack, stroke, or blood clot.




FDA pregnancy category C. It is not known whether anti-inhibitor coagulant complex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether anti-inhibitor coagulant complex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.


How should I use Autoplex T (anti-inhibitor coagulant complex)?


Anti-inhibitor coagulant complex is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.


Anti-inhibitor coagulant complex is usually given once every 6 to 12 hours until your condition improves.


Anti-inhibitor coagulant complex is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.


Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.


Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder. Store anti-inhibitor coagulant complex in a refrigerator. Do not freeze. Take the vial out of the refrigerator and allow it to reach room temperature before mixing with the diluent. Do not heat the medicine. You may store this medicine at room temperature for up to 6 months or until the expiration date on the label. After mixing anti-inhibitor coagulant complex with the diluent, store the mixture at room temperature and use it within 3 hours. Do not refrigerate mixed medicine.

What happens if I miss a dose?


Call your doctor for instructions if you miss a dose of anti-inhibitor coagulant complex.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.


What should I avoid while using Autoplex T (anti-inhibitor coagulant complex)?


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


Autoplex T (anti-inhibitor coagulant complex) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), feeling like you might pass out;




  • fever, chills, runny nose, and drowsiness, followed by rash and joint pain about 2 weeks later;




  • sudden numbness or weakness, especially on one side of the body;




  • sudden severe headache, confusion, problems with vision, speech, or balance;




  • pain, swelling, warmth, or redness in one or both legs;




  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;




  • fast or slow heart rate, weak pulse, trouble breathing, chest pain or cough; or




  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • pain around the IV needle or




  • numbness or tingling, especially in your face.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Autoplex T (anti-inhibitor coagulant complex)?


The following drugs should not be given within 12 hours after you receive anti-inhibitor coagulant complex.



  • aminocaproic acid (Amicar);




  • desmopressin (DDAVP); or




  • tranexamic acid (Cyklokapron, Lysteda).



This list is not complete and other drugs may interact with anti-inhibitor coagulant complex. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Autoplex T resources


  • Autoplex T Use in Pregnancy & Breastfeeding
  • Autoplex T Drug Interactions
  • Autoplex T Support Group
  • 0 Reviews for Autoplex T - Add your own review/rating


  • Autoplex T Advanced Consumer (Micromedex) - Includes Dosage Information

  • Anti-Inhibitor Coagulant Complex Professional Patient Advice (Wolters Kluwer)

  • Anti-inhibitor Coagulant Complex Monograph (AHFS DI)

  • Anti-Inhibitor Coagulant Complex MedFacts Consumer Leaflet (Wolters Kluwer)

  • FEIBA NF Prescribing Information (FDA)



Compare Autoplex T with other medications


  • Hemophilia A


Where can I get more information?


  • Your doctor or pharmacist can provide more information about anti-inhibitor coagulant complex.


Monday, 10 September 2012

Anusol Ointment





1. Name Of The Medicinal Product



Anusol Ointment


2. Qualitative And Quantitative Composition



Each 100g ointment contains:



Zinc Oxide 10.75 g



Bismuth Subgallate 2.25 g



Balsam Peru 1.875 g



Bismuth Oxide 0.875 g



3. Pharmaceutical Form



A light buff coloured ointment.



4. Clinical Particulars



4.1 Therapeutic Indications



Symptomatic relief of uncomplicated internal and external haemorrhoids, pruritus ani, proctitis and fissures. Also indicated post operatively in ano-rectal surgical procedures and after incision of thrombosed or sclerosed ano-rectal veins.



Anusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.



4.2 Posology And Method Of Administration



Topical.



Adults and Elderly (over 65 years): Apply to the affected area at night, in the morning and after each evacuation until the condition is controlled. Thoroughly cleanse the affected area, dry and apply ointment. Anusol Ointment should be applied on a gauze dressing. For internal conditions use rectal nozzle provided. Remove the nozzle cap. Clean the nozzle after each use. Not to be taken orally.



Children: Not recommended



4.3 Contraindications



Known hypersensitivity to any of the constituents.



4.4 Special Warnings And Precautions For Use



None known.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



None known.



4.6 Pregnancy And Lactation



Whilst formal studies on the effect of this product during pregnancy have not been conducted, there is no epidemiological evidence of adverse effects either to the pregnant mother or foetus.



4.7 Effects On Ability To Drive And Use Machines



None known.



4.8 Undesirable Effects



Rarely, sensitivity reactions. Patients may occasionally experience transient burning on application, especially if the anoderm is not intact.



4.9 Overdose



Treatment of a large acute overdose should include gastric lavage, purgation with magnesium sulphate and complete bed rest. If necessary, apply oxygen and give general supportive measures.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Anusol Ointment provides antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions.



Bismuth Oxide is weakly astringent with supposed antiseptic properties and has a protective action on mucous membranes and raw surfaces.



Zinc Oxide is an astringent and mild antiseptic and probably owes its actions to the ability of the zinc ion to precipitate protein but other mechanisms may be involved. Zinc Oxide is also used to absorb skin moisture and decrease friction and discourage growth of certain bacteria.



Balsam Peru has a very mild antiseptic action by virtue of its content of cinnamic and benzoic acids. It is believed to promote the growth of epithelial cells.



5.2 Pharmacokinetic Properties



The active ingredients exert their therapeutic effect without being absorbed into the systemic circulation. These observations are supported by evidence from various studies and reviews.



5.3 Preclinical Safety Data



The active ingredients of Anusol are well known constituents of medicinal products and their safety profile is well documented.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Anusol Ointment contains the following excipients:-



Magnesium stearate



Cocoa butter



Lanolin anhydrous



Castor oil



Kaolin light



Petroleum Jelly White



6.2 Incompatibilities



None known.



6.3 Shelf Life



Not less than 3 years when stored in the original packing.



6.4 Special Precautions For Storage



Do not store above 25° C.



6.5 Nature And Contents Of Container



Externally printed and internally lacquered 25 g aluminium tube with plastic cap. A plastic nozzle with cap is also provided for internal application.



6.6 Special Precautions For Disposal And Other Handling



No special requirements.



Administrative Data


7. Marketing Authorisation Holder



McNeil Products Limited



Foundation Park



Roxborough Way



Maidenhead



Berkshire



SL6 3UG



United Kingdom



8. Marketing Authorisation Number(S)



15513/0042



9. Date Of First Authorisation/Renewal Of The Authorisation



14 March 1997



10. Date Of Revision Of The Text



25 February 2008




Sunday, 9 September 2012

Clobex


Generic Name: clobetasol topical (kloe BAY ta sol)

Brand Names: Clobevate, Clobex, Cormax, Embeline E, Olux, Olux-E, Temovate


What is Clobex (clobetasol topical)?

Clobetasol is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


Clobetasol topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Clobetasol topical may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Clobex (clobetasol topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with clobetasol topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Do not use this medication on a child without medical advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

What should I discuss with my healthcare provider before using Clobex (clobetasol topical)?


Do not use this medication if you are allergic to clobetasol.

To make sure you can safely take clobetasol topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection.


Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.


FDA pregnancy category C. It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether clobetasol topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without medical advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

How should I use Clobex (clobetasol topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Wash your hands before and after using clobetasol topical, unless you are using the medication to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not use this medication over a large area of skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with clobetasol topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection. It is important to use clobetasol topical regularly to get the most benefit.

If you use this medication long-term, your blood will need to be tested often. Visit your doctor regularly.


Store at room temperature away from moisture and heat. Keep from freezing.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of clobetasol is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using Clobex (clobetasol topical)?


Clobetasol topical should not be used to treat any skin condition your doctor has not prescribed it for.


Avoid using clobetasol topical to treat skin on your face, underarms, or groin area without your doctor's advice. Avoid getting this medication in your eyes. If contact does occur, rinse with water. Do not use clobetasol topical on broken or infected skin. Also avoid using this medication in open wounds.

Clobex (clobetasol topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.


Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:

  • blurred vision, or seeing halos around lights;




  • mood changes;




  • sleep problems (insomnia);




  • weight gain, puffiness in your face; or




  • muscle weakness, feeling tired.



Less serious side effects may include:



  • mild skin rash, itching, burning, or redness;




  • dry or cracking skin;




  • thinning or softening of your skin;




  • skin rash or irritation around your mouth;




  • swollen hair follicles;




  • temporary hair loss;




  • spider veins;




  • changes in color of treated skin;




  • blisters, pimples, or crusting of treated skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Clobex (clobetasol topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied clobetasol topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Clobex resources


  • Clobex Side Effects (in more detail)
  • Clobex Use in Pregnancy & Breastfeeding
  • Clobex Drug Interactions
  • Clobex Support Group
  • 16 Reviews for Clobex - Add your own review/rating


  • Clobex Prescribing Information (FDA)

  • Clobex Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Clobex Advanced Consumer (Micromedex) - Includes Dosage Information

  • Cormax Prescribing Information (FDA)

  • Embeline Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Olux Prescribing Information (FDA)

  • Olux Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Olux-E Prescribing Information (FDA)

  • Olux-E Emollient Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Temovate Prescribing Information (FDA)



Compare Clobex with other medications


  • Atopic Dermatitis
  • Dermatitis
  • Lichen Planus
  • Lichen Sclerosus
  • Psoriasis


Where can I get more information?


  • Your pharmacist can provide more information about clobetasol topical.

See also: Clobex side effects (in more detail)