Saturday, 6 October 2012

Neutrogena T/Gel


Generic Name: coal tar topical (KOL TAR TOP ik al)

Brand Names: Balnetar, Betatar Gel, Coal Tar, Cutar, Denorex, Denorex Dry Scalp, Denorex Extra Strength, Denorex Medicated Shampoo and Conditioner, DHS Tar Shampoo, Doak Tar, Doak Tar Oil, Elta Tar, Fototar, G-TAR, Ionil T, Ionil T Plus, MG 217 Psoriasis, MG217 Medicated Tar, Neutrogena T/Derm, Neutrogena T/Gel, Neutrogena T/Gel Extra Strength, Oxipor VHC, PC Tar, Pentrax, Pentrax Gold, Polytar, Psoriasin, Psorigel, T/Gel Conditioner, Tegrin Medicated, Tegrin Medicated Soap, Therapeutic, Theraplex T, Zetar


What is coal tar?

Coal tar is a by-product of coal processing.


Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


Coal tar may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


What should I discuss with my health care provider before using coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether coal tar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients.


How should I use coal tar?


Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.


Apply coal tar cream, lotion, ointment, or solution according the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day.


To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall.


Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar shampoo may discolor blond or colored hair. This effect is usually temporarily.


Some forms of coal tar can stain fabric or other surfaces.


Store coal tar at room temperature away from moisture and heat. Keep the medicine tightly closed with not in use.

What happens if I miss a dose?


Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a coal tar overdose are not known.


What should I avoid while using coal tar?


Avoid getting this medication in your eyes. If this does occur, rinse with water.

Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result.

Coal tar side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin.

Less serious side effects may include mild skin irritation or skin rash.


This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect coal tar?


Do not use coal tar together with other psoriasis medications unless your doctor tells you to.

There may be other drugs that can interact with coal tar. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Neutrogena T/Gel resources


  • Neutrogena T/Gel Use in Pregnancy & Breastfeeding
  • Neutrogena T/Gel Support Group
  • 0 Reviews for Neutrogena T/Gel - Add your own review/rating


  • Neutrogena T/Gel Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Coal Tar Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Denorex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Doak Tar Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Fototar Ointment MedFacts Consumer Leaflet (Wolters Kluwer)

  • MG217 Medicated Tar Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Psoriasin Prescribing Information (FDA)



Compare Neutrogena T/Gel with other medications


  • Dermatitis
  • Psoriasis
  • Seborrheic Dermatitis


Where can I get more information?


  • Your pharmacist can provide more information about coal tar.


Wednesday, 3 October 2012

Prialt


Pronunciation: zye-KOE-noe-tide
Generic Name: Ziconotide
Brand Name: Prialt

Treatment with Prialt may cause severe psychiatric and neurological problems. Patients with a history of psychosis should not receive Prialt. You will be monitored often for evidence of thinking problems, hallucinations, or changes in mood or consciousness. If these symptoms occur, Prialt can be stopped without causing withdrawal effects.





Prialt is used for:

Managing severe chronic pain in patients who cannot take medicine by mouth or do not respond well to other treatments.


Prialt is an N-type calcium channel blocker. It works by targeting and blocking N-type calcium channels on nerves that transmit pain signals.


Do NOT use Prialt if:


  • you are allergic to any ingredient in Prialt

  • you have a history of psychosis

  • you have an infection at the injection site or a damaged spinal canal that interferes with circulation of cerebral spinal fluid

  • you have a bleeding disorder

Contact your doctor or health care provider right away if any of these apply to you.



Before using Prialt:


Some medical conditions may interact with Prialt. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, plan to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have or have a history of depression or have ever considered suicide

  • if you have kidney problems

Some MEDICINES MAY INTERACT with Prialt. However, no specific interactions with Prialt are known at this time.


This may not be a complete list of all interactions that may occur. Ask your health care provider if Prialt may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Prialt:


Use Prialt as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Prialt is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor if you have any questions about Prialt.

  • If you miss a dose of Prialt, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Prialt.



Important safety information:


  • Prialt may cause drowsiness, dizziness, or decreased alertness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Prialt. Using Prialt alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Prialt. Prialt will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.

  • Prialt is not an opiate and cannot prevent or reduce symptoms of opiate withdrawal. Talk with your doctor about withdrawal from opiate treatment.

  • LAB TESTS, including kidney function tests, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.

  • Prialt is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Prialt during pregnancy. It is unknown if Prialt is excreted in breast milk. Do not breast-feed while using Prialt.


Possible side effects of Prialt:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Abnormal walking; back pain; bad taste in mouth; burning, aching, tingling sensation on the skin; constipation; diarrhea; dizziness; dry skin; feeling of a whirling motion; incoordination; increased cough; loss of appetite; muscle tension; pain; pain at insertion site; rapid, jerky eye movements; ringing in the ears; runny nose; skin irritation; sleepiness; sore throat; stomach pain; sweating; vision changes.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal thinking; anxiety; change in mental state (eg, lack of energy, confusion, disorientation); change in mood or perception (eg, hallucinations; unusual sensations in the mouth; paranoia; hostility; delirium; manic reactions; psychosis); chest pain; dark urine; depression; fainting; fever; flu-like symptoms; headache; inability to empty the bladder; memory problems or memory loss; muscle cramps; muscle or joint pain; nausea; nervousness; pounding in the chest; seizures; speech problems; stiff neck; stupor; suicidal thoughts or behaviors; unresponsiveness; urination problems; vomiting; weakness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Prialt side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; dizziness; drowsiness; garbled speech; loss of coordination; muscle twitching; nausea; rapid eye movement; stupor; unresponsiveness.


Proper storage of Prialt:

Store Prialt as directed on the prescription label. Keep Prialt out of the reach of children and away from pets.


General information:


  • If you have any questions about Prialt, please talk with your doctor, pharmacist, or other health care provider.

  • Prialt is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Prialt. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Prialt resources


  • Prialt Side Effects (in more detail)
  • Prialt Use in Pregnancy & Breastfeeding
  • Prialt Drug Interactions
  • Prialt Support Group
  • 0 Reviews for Prialt - Add your own review/rating


  • Prialt Prescribing Information (FDA)

  • Prialt Consumer Overview

  • Prialt Monograph (AHFS DI)

  • Prialt Advanced Consumer (Micromedex) - Includes Dosage Information

  • Ziconotide Professional Patient Advice (Wolters Kluwer)



Compare Prialt with other medications


  • Pain

Monday, 1 October 2012

Childrens Ibuprofen Berry


Generic Name: ibuprofen (EYE bue PROE fen)

Brand Names: Advil, Advil Childrens, Advil Junior Strength, Advil Liquigel, Advil Migraine, Advil Pediatric, Children's Ibuprofen Berry, Genpril, IBU, Midol IB, Midol Maximum Strength Cramp Formula, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Nuprin


What is Childrens Ibuprofen Berry (ibuprofen)?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.


Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury.


Ibuprofen may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Childrens Ibuprofen Berry (ibuprofen)?


This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.


This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.

Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.


Do not take more of this medication than is recommended. An overdose of ibuprofen can cause damage to your stomach or intestines. Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever.

What should I discuss with my healthcare provider before taking Childrens Ibuprofen Berry (ibuprofen)?


Do not use ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).


This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen, especially in older adults.


You should not use this medication if you are allergic to ibuprofen, aspirin or other NSAIDs.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:



  • a history of heart attack, stroke, or blood clot;




  • heart disease, congestive heart failure, high blood pressure;




  • a history of stomach ulcers or bleeding;




  • asthma;




  • polyps in your nose;



  • liver or kidney disease;


  • systemic lupus erythematosus (SLE);




  • a bleeding or blood clotting disorder; or




  • if you smoke.




FDA pregnancy category D. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using ibuprofen. It is not known whether ibuprofen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child without the advice of a doctor.

How should I take Childrens Ibuprofen Berry (ibuprofen)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Do not take more of this medication than is recommended. An overdose of ibuprofen can cause damage to your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of ibuprofen needed to get relief from your pain, swelling, or fever. Take ibuprofen with food or milk to lessen stomach upset. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The ibuprofen chewable tablet must be chewed before you swallow it.


If you take ibuprofen for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.


Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

What happens if I miss a dose?


Since ibuprofen is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.

What should I avoid while taking Childrens Ibuprofen Berry (ibuprofen)?


Avoid taking ibuprofen if you are taking aspirin to prevent stroke or heart attack. Ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin (non-enteric coated form). Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Ibuprofen and other NSAIDs are contained in many combination medicines. Taking certain products together can cause you to get too much ibuprofen. Check the label to see if a medicine contains ibuprofen or similar NSAIDs (aspirin, naproxen, ketoprofen). Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Childrens Ibuprofen Berry (ibuprofen) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking ibuprofen and seek medical attention or call your doctor at once if you have any of these serious side effects:

  • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;




  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;




  • swelling or rapid weight gain;




  • urinating less than usual or not at all;




  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;




  • bruising, severe tingling, numbness, pain, muscle weakness; or




  • severe headache, neck stiffness, chills, increased sensitivity to light, and/or seizure (convulsions).



Less serious side effects may include:



  • upset stomach, mild heartburn, diarrhea, constipation;




  • bloating, gas;




  • dizziness, headache, nervousness;




  • skin itching or rash;




  • blurred vision; or




  • ringing in your ears.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Childrens Ibuprofen Berry (ibuprofen)?


Ask your doctor before using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all other medicines you use, especially:



  • aspirin or other NSAIDs such as naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;




  • heart or blood pressure medicine such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;




  • lithium (Eskalith, Lithobid);




  • diuretics (water pills) such as furosemide (Lasix);




  • methotrexate (Rheumatrex, Trexall);




  • steroids (prednisone and others); or




  • a blood thinner such as warfarin (Coumadin, Jantoven).



This list is not complete and other drugs may interact with ibuprofen. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Childrens Ibuprofen Berry resources


  • Childrens Ibuprofen Berry Side Effects (in more detail)
  • Childrens Ibuprofen Berry Use in Pregnancy & Breastfeeding
  • Childrens Ibuprofen Berry Drug Interactions
  • Childrens Ibuprofen Berry Support Group
  • 0 Reviews for Childrens Ibuprofen Berry - Add your own review/rating


Compare Childrens Ibuprofen Berry with other medications


  • Fever
  • Pain
  • Spondylolisthesis


Where can I get more information?


  • Your pharmacist can provide more information about ibuprofen.

See also: Childrens Ibuprofen Berry side effects (in more detail)


Wednesday, 26 September 2012

Sennosides Granules



Pronunciation: SEN-oh-sides
Generic Name: Sennosides
Brand Name: Senokot


Sennosides Granules are used for:

Treating constipation.


Sennosides Granules are a stimulant laxative. It works by irritating bowel tissues, resulting in bowel movements.


Do NOT use Sennosides Granules if:


  • you are allergic to any ingredient in Sennosides Granules

  • you have had recent abdominal surgery or require immediate abdominal surgery

  • you have appendicitis; bleeding of the stomach, intestine, or rectum; or an obstruction in your intestines (fecal impaction)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Sennosides Granules:


Some medical conditions may interact with Sennosides Granules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have congestive heart failure, you are experiencing nausea or vomiting, or you have undiagnosed stomach pain

Some MEDICINES MAY INTERACT with Sennosides Granules. However, no specific interactions with Sennosides Granules are known at this time.


Ask your health care provider if Sennosides Granules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Sennosides Granules:


Use Sennosides Granules as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Sennosides Granules by mouth with or without food.

  • Take Sennosides Granules with a full glass of water (8 oz/240 mL). Drinking extra fluids while you are taking Sennosides Granules are recommended. Check with your doctor for instructions.

  • It is best to take Sennosides Granules at bedtime.

  • If you miss a dose of Sennosides Granules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sennosides Granules.



Important safety information:


  • A bowel movement usually occurs in 6 to 12 hours.

  • Do not use for longer than 1 week without checking with your doctor.

  • Using Sennosides Granules for a long time may result in loss of normal bowel function.

  • Do not take additional laxatives or stool softeners with Sennosides Granules unless directed by your doctor.

  • If you notice a sudden change in bowel habits that lasts for 2 weeks or more, stop using Sennosides Granules and check with your doctor.

  • Sennosides Granules may discolor the urine pink to red, or yellow to brown.

  • Sennosides Granules should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sennosides Granules while you are pregnant. It is not known if Sennosides Granules are found in breast milk. If you are or will be breast-feeding while you use Sennosides Granules, check with your doctor. Discuss any possible risks to your baby.

Overuse of laxatives can lead to a DEPENDENCE on laxatives to have a bowel movement. In severe overuse cases, some laxatives have caused damage to the intestines and bowel.



Possible side effects of Sennosides Granules:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Abdominal discomfort or cramping; diarrhea; nausea.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); kidney inflammation; poor bowel function; rectal bleeding.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Sennosides side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately.


Proper storage of Sennosides Granules:

Store Sennosides Granules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep Sennosides Granules out of the reach of children and away from pets.


General information:


  • If you have any questions about Sennosides Granules, please talk with your doctor, pharmacist, or other health care provider.

  • Sennosides Granules are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sennosides Granules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sennosides resources


  • Sennosides Side Effects (in more detail)
  • Sennosides Use in Pregnancy & Breastfeeding
  • Drug Images
  • Sennosides Drug Interactions
  • Sennosides Support Group
  • 6 Reviews for Sennosides - Add your own review/rating


Compare Sennosides with other medications


  • Bowel Preparation
  • Constipation

Saturday, 22 September 2012

Aqueous Iodine Oral Solution BP





1. Name Of The Medicinal Product



Aqueous Iodine Oral Solution BP


2. Qualitative And Quantitative Composition



Iodine BP 5.0% w/v



Potassium Iodide BP 10.0% w/v



3. Pharmaceutical Form



Oral Solution



4. Clinical Particulars



4.1 Therapeutic Indications



For use in the pre-operative management of hyperthyroidism.



4.2 Posology And Method Of Administration



Oral.



Dose: adults, children and the elderly: 0.1 – 0.3ml well diluted in milk or water.



Dosage schedule: to be taken three times a day for six days.



4.3 Contraindications



Contraindicated for patients hypersensitive to iodine or iodides, and use in pregnancy and lactation.



4.4 Special Warnings And Precautions For Use



Should not be used for long term treatment.



Dispensing pack-not for retail sale.



Keep all medicines away from children.



Use with caution in children.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



Administration of this product may interfere with tests of thyroid function.



4.6 Pregnancy And Lactation



Not to be used during pregnancy and lactation. Iodides cross the placenta and are excreted in breast milk. There is a possibility of goitre in infants of mothers taking iodides.



4.7 Effects On Ability To Drive And Use Machines



None known.



4.8 Undesirable Effects



May cause allergic reactions, including urticaria, angioedema, cutaneous haemorrhage or purpuras, fever, arthralgia, lymphadenopathy and eosinophilia, coryza-like symptoms, headache, lachrymation, conjunctivitis, laryngitis, bronchitis, and pain in the salivary glands. In addition to the above, use may lead to adverse effects on the mouth such as metallic taste, increased salivation, burning or pain. Swelling and inflammation of the throat, acneform skin disorders, depression, insomnia, impotence and diarrhoea (which may be bloody) can also result.



4.9 Overdose



Symptoms of acute poisoning from ingestion of iodine include a disagreeable metallic taste, vomiting, abdominal pain and diarrhoea may occur. Renal failure may occur 1-3 days later. Death may be caused by circulatory failure, swelling of the epiglottis causing asphyxia, aspiration, pneumonia or pulmonary oedema. Oesophageal stricture may occur if the patient survives the acute stage. The fatal dose of iodine is 2 to 3g. Symptomatic treatment for allergic reactions and iodism may be required, although symptoms usually subside rapidly when administration of iodine or iodide is stopped. In acute poisoning copious draughts of milk and starch mucilage should be given. If there is no oesophageal damage the stomach may be emptied by aspiration and lavage with dilute starch mucilage or a 1% solution of sodium thiosulphate. Use of gastric lavage with activated charcoal has also been suggested. Electrolyte and water losses should be replaced and the circulation should be maintained. Pethidine or morphine sulphate may be given for pain, under medical supervision. A tracheotomy may become necessary.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Iodine and iodides are used in the pre-operative treatment of hyperthyroidism in conjunction with antithyroid agents. The patient is rendered euthyroid with an antithyroid agent and iodine or iodides are added to the therapy before subtotal thyroidectomy. Iodine aqueous solution is given to render the thyroid firm and avoid the increased vascularity and friability with increased risk of haemorrhage that may result from the use of an antithyroid agent alone.



5.2 Pharmacokinetic Properties



Iodine is converted to iodide, which is trapped in the thyroid gland.



Iodides are excreted mainly in the urine with smaller amounts excreted in the faeces, sweat and saliva. They cross the placenta and are excreted in breast milk.



5.3 Preclinical Safety Data



No data of relevance which is additional to that included on other sections of the SPC.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Purified water BP



6.2 Incompatibilities



None known.



6.3 Shelf Life



100ml: 36 months unopened.



500ml: 36 months unopened.



6.4 Special Precautions For Storage



Store below 25°C.



6.5 Nature And Contents Of Container



100ml: amber glass bottle, plastic cap.



500ml: amber glass bottle, plastic cap.



6.6 Special Precautions For Disposal And Other Handling



None



7. Marketing Authorisation Holder



Thornton & Ross Ltd.,



Linthwaite Laboratories



Huddersfield



HD7 5QH



8. Marketing Authorisation Number(S)



PL 00240/6170R



9. Date Of First Authorisation/Renewal Of The Authorisation



04.12.98



10. Date Of Revision Of The Text



12.11.01



11 DOSIMETRY (IF APPLICABLE)


Not Applicable



12 INSTRUCTIONS FOR PREPARATION OF RADIOPHARMACEUTICALS (IF APPLICABLE)


Not Applicable




Friday, 21 September 2012

levofloxacin Ophthalmic



lee-voe-FLOX-a-sin


Commonly used brand name(s)

In the U.S.


  • Iquix

  • Quixin

Available Dosage Forms:


  • Solution

Therapeutic Class: Antibiotic


Chemical Class: Fluoroquinolone


Uses For levofloxacin


Ophthalmic levofloxacin is used in the eye to treat bacterial infections of the eye. Ophthalmic levofloxacin works by killing bacteria.


levofloxacin is available only with your doctor's prescription.


Before Using levofloxacin


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For levofloxacin, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to levofloxacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Use is not recommended in infants under 1 year of age. In children older than 1 year, levofloxacin is not expected to cause different side effects or problems than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of levofloxacin in the elderly with use in other age groups, levofloxacin is not expected to cause different side effects or problems in older people than it does in younger adults.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking levofloxacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using levofloxacin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Cisapride

  • Dronedarone

  • Mesoridazine

  • Pimozide

  • Sparfloxacin

  • Thioridazine

Using levofloxacin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Acecainide

  • Acetohexamide

  • Alfuzosin

  • Amiodarone

  • Amitriptyline

  • Amoxapine

  • Apomorphine

  • Arsenic Trioxide

  • Asenapine

  • Astemizole

  • Azimilide

  • Azithromycin

  • Benfluorex

  • Bretylium

  • Chloroquine

  • Chlorpromazine

  • Chlorpropamide

  • Ciprofloxacin

  • Citalopram

  • Clarithromycin

  • Clomipramine

  • Clozapine

  • Crizotinib

  • Dasatinib

  • Desipramine

  • Disopyramide

  • Dofetilide

  • Dolasetron

  • Droperidol

  • Erythromycin

  • Flecainide

  • Fluconazole

  • Gatifloxacin

  • Gemifloxacin

  • Gliclazide

  • Glimepiride

  • Glipizide

  • Gliquidone

  • Glyburide

  • Granisetron

  • Guar Gum

  • Halofantrine

  • Haloperidol

  • Ibutilide

  • Iloperidone

  • Imipramine

  • Insulin

  • Insulin Aspart, Recombinant

  • Insulin Glulisine

  • Insulin Lispro, Recombinant

  • Lapatinib

  • Lopinavir

  • Lumefantrine

  • Mefloquine

  • Metformin

  • Methadone

  • Miglitol

  • Moricizine

  • Moxifloxacin

  • Nilotinib

  • Norfloxacin

  • Nortriptyline

  • Octreotide

  • Ofloxacin

  • Paliperidone

  • Pazopanib

  • Perflutren Lipid Microsphere

  • Perphenazine

  • Posaconazole

  • Procainamide

  • Prochlorperazine

  • Promethazine

  • Propafenone

  • Protriptyline

  • Quetiapine

  • Quinidine

  • Quinine

  • Ranolazine

  • Salmeterol

  • Saquinavir

  • Sematilide

  • Sodium Phosphate

  • Sodium Phosphate, Dibasic

  • Sodium Phosphate, Monobasic

  • Solifenacin

  • Sorafenib

  • Sotalol

  • Sunitinib

  • Tedisamil

  • Telavancin

  • Telithromycin

  • Terfenadine

  • Tetrabenazine

  • Theophylline

  • Tolazamide

  • Tolbutamide

  • Toremifene

  • Trazodone

  • Trifluoperazine

  • Trimipramine

  • Troglitazone

  • Vandetanib

  • Vardenafil

  • Vemurafenib

  • Voriconazole

  • Warfarin

  • Ziprasidone

Using levofloxacin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Betamethasone

  • Corticotropin

  • Cortisone

  • Cosyntropin

  • Deflazacort

  • Dexamethasone

  • Fludrocortisone

  • Fluocortolone

  • Hydrocortisone

  • Methylprednisolone

  • Paramethasone

  • Prednisolone

  • Prednisone

  • Triamcinolone

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Proper Use of levofloxacin


Dosing


The dose of levofloxacin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of levofloxacin. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


To use levofloxacin ophthalmic solution (eye drops):


  • First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.

  • If you think you did not get the drop of medicine into your eyes properly, use another drop.

  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

  • For ophthalmic solution dosage form:
    • For bacterial conjunctivitis:
      • Adults and children 1 year of age and older—Days 1 and 2: Put one to two drops in the affected eye(s) every two hours while awake. Do not put drops in more than 8 times a day. Days 3 through 7: Put one to two drops in the affected eye(s) every 4 hours while awake. Do not put drops in more than 4 times a day.

      • Infants and children up to 1 year of age—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of levofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using levofloxacin


If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.


levofloxacin may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.


levofloxacin Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • voice changes

  • body aches or pain

  • congestion

  • dryness or soreness of throat

  • runny nose

  • swelling of the eyelid

  • tender, swollen glands in neck

  • trouble in swallowing

  • Itching, pain, redness or swelling of eye or eyelid

  • watering of eyes

  • decreased vision

  • fever

  • feeling of having something in the eye

  • headache

  • hoarseness

  • eye burning, dryness, itching, or pain

  • increased sensitivity of eyes to light

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



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More levofloxacin Ophthalmic resources


  • Levofloxacin Ophthalmic Use in Pregnancy & Breastfeeding
  • Levofloxacin Ophthalmic Support Group
  • 0 Reviews for Levofloxacin Ophthalmic - Add your own review/rating


  • levofloxacin ophthalmic Concise Consumer Information (Cerner Multum)

  • Iquix Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Iquix Prescribing Information (FDA)

  • Quixin Prescribing Information (FDA)

  • Quixin eent Monograph (AHFS DI)

  • Quixin Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare levofloxacin Ophthalmic with other medications


  • Conjunctivitis, Bacterial
  • Ophthalmic Surgery

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